Patterns of TPD52 overexpression in multiple human solid tumor types analyzed by quantitative PCR
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چکیده
منابع مشابه
Patterns of TPD52 overexpression in multiple human solid tumor types analyzed by quantitative PCR.
Tumor protein D52 (TPD52) is located at chromosome 8q21, a region that is frequently gained or amplified in multiple human cancer types. TPD52 has been suggested as a potential target for new anticancer therapies. In order to analyze TPD52 expression in the most prevalent human cancer types, we employed quantitative PCR to measure TPD52 mRNA levels in formalin-fixed tissue samples from more tha...
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Gains in the long arm of chromosome 8 (8q) are believed to be associated with poor outcome and the development of hormone-refractory prostate cancer. Based on a meta-analysis of gene expression microarray data from multiple prostate cancer studies (D. R. Rhodes et al., Cancer Res 2002;62:4427-33), a candidate oncogene, Tumor Protein D52 (TPD52), was identified in the 8q21 amplicon. TPD52 is a c...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2013
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.2013.2200